June 5, 2026

Platelet Rich Fibrin (PRF) Aftercare

Written by Dr Kate Jameson

preparing prp

Disclaimer:
The following information is provided for educational purposes only and is intended for existing Youth Lab clients who have already undergone a consultation and treatment with one of our medical practitioners. 

This content is not an advertisement and should not be interpreted as promoting or encouraging the use of prescription-only medicines or regulated medical treatments.

Individual suitability for any medical or cosmetic procedure can only be determined following a face-to-face consultation with a qualified practitioner.

All treatments discussed are performed under appropriate medical supervision in accordance with Australian regulations.

For personalised advice, assessment, or further clarification, please contact Youth Lab directly.

Thank you for attending Youth Lab for your PRP or PRF Treatment. Please take the time to carefully read the post-treatment guidance below. All aftercare has also been provided via email and is accessible via your online Youth Lab Profile. 

The information below is intended for existing Youth Lab clients who have undergone a PRP or PRF treatment following consultation with one of our medical practitioners. It is provided for educational purposes only and should not be considered medical advice or promotion of any prescription-only medicine.

POST-TREATMENT INSTRUCTIONS

  • Avoid any heat-inducing activities for 24 hours.
  • Do not perform strenuous exercise for 24 hours. 
  • Avoid pressure on the area for 48 hours (i.e. avoid face-down massages).
  • Do not massage the treatment area unless instructed to do so.
  • Avoid alcohol for 24 hours.
  • Avoid active cosmeceutical products (AHAs, retinol, vitamin C) for 24 hours.
  • Do not apply oil-based makeup for 24 hours. 
  • Use a topical treatment to soothe the skin such as Bepanthen or Arnica cream.
  • Avoid facial treatments for 2 weeks (including facials, waxing, chemical peels, skin needling, Hydrafacial, IPL or laser)
  • Avoid blood thinning medication such as Aspirin & Ibuprofen for 7 days (unless medically necessary)

WHAT TO EXPECT: 

The listed below are all normal side effects and should self resolve within a few days. 

  • Swelling, significant in some cases
  • Redness 
  • Tenderness 
  • Bruising 
  • Lumps 

Swelling

There may be swelling in the treated area. This is a normal result of the injections and will generally disappear within a few days. PRP or PRF to the eyes can cause significant swelling due to the volume of PRP/PRF injected, this is normal. 

If symptoms persist for over 7 days or other reactions occur, please contact the clinic. Swelling may appear asymmetrical, this is normal. 

Swelling Relief

  • Apply a cool compress to the area for 10 minutes every hour on treatment day.
  • Take an antihistamine (e.g. 10mg loratadine)
  • Try sleeping on your back, slightly elevated, to prevent pressure build-up on the face 

Bruising

Bruising is a common and expected side effect with any injectable treatment. Bruising is not due to poor technique and will not alter the final result of your treatment. In order to reduce bruising it is important to adhere to the aftercare regime.

Bruising Relief 

  • Avoid any medications containing NSAIDs, aspirin, vitamin E and ginseng for the week prior and the week following treatment, unless medically necessary and after discussion with your doctor/nurse.
  • Apply a cool compress to the area for 10 minutes every hour on treatment day.
  • Apply topical Arnica or Hirudoid cream to the affected area. 

We offer HEALITE II LED treatments for those cases where bruising is severe. 

Other 

There may be small lumps, these generally disappear as the PRP/PRF integrates into the skin over the days after treatment. Please contact the clinic if they do not disappear. 

Rarer side effects have been discussed in the consultation process and are not expected with every treatment.

More severe complications may include:

  • Allergic reaction (difficulty breathing, rapid heart beat, rash) 
  • Nerve injury resulting in numbness, pain or muscle dysfunction 

If you experience any of the above severe complications please contact the clinic on (08) 9324 1604 (West Perth), (08) 9260 6800 (Claremont), (08) 9260 6880 (Joondalup), (08) 9260 6820 (Applecross) or (08) 9260 6855 (Dunsborough)

If it is after hours (between 5pm and 9am) please email our emergency email at emergency@youthlab.com.au. This email address is only to be used in cases of severe side effects. 

Please note this email may not be seen between the hours of 9pm and 7am so if any concerns arise during this time or if there is a high level of concern after hours present to your nearest emergency department or call 000.

Additional 

As with any cosmetic medical treatment, rare risks and complications may occur, including those discussed with you during your consultation. If you experience anything unexpected, have concerns about your healing, or feel uncertain about your recovery at any point, please do not hesitate to contact the clinic. We are here to support you and would always rather hear from you early. Please ensure you attend your scheduled follow-up appointment so that your practitioner can review your results and address any questions you may have.

Please contact the clinic on (08) 9324 1604 (West Perth), (08) 9260 6800 (Claremont), (08) 9260 6880 (Joondalup), (08) 9260 6820 (Applecross) or (08) 9260 6855 (Dunsborough) if you have any questions about your treatment or aftercare instructions.