February 20, 2024

Learn about Polynucleotides with Nurse Lizzie

Written by Team Youth Lab

In the ever-evolving world of aesthetic medicine, the quest for facial rejuvenation techniques and advancements continue and Korea has delivered a polynucleotide biostimulator “Rejuran”. This injectable treatment has only recently been approved in Australia, it promotes collagen production and revitalises the skin. So what are we waiting for… let’s delve into the science behind the newest innovative approach to facial aesthetics. 

Down to the science 

Polynucleotide biostimulator injectables are classed as a medical device; they are a completely different product compared to the traditional dermal filler/collagen stimulating treatments we perform. This product is derived from slow degrading fresh salmon DNA fragments using DOT technology to extract the DNA which is mirroring human DNA, 97% similar to humans. Renowned for their regenerative properties, polynucleotides have the ability to promote tissue repair, stimulate cellular regeneration and tissue remodelling.

Collagen stimulation diminishes as we age, this protein is responsible for skin laxity and firmness which in turn causes fine lines, increased laxity/sag to the skin. This is when polynucleotides work by activating fibroblast cells that are responsible for the scaffolding and collagen formation thereby assisting with the regeneration of volume and firmness to the skin and increasing that collagen bank! 

Skin texture and tone is another concern which can get a helping hand from this new treatment. Beyond the collagen stimulation, this treatment can help enhance circulation and improve overall radiance by increasing blood flow to the skin. The pure DNA helps to oxygenate the areas of concern to reduce signs of dullness and fatigue. This will help signs of dullness and even assist with uneven tone such as pigmentation. These regenerative properties can penetrate deep to help with the cellular turnover of your cells to offer targeted collagen for facial rejuvenation from within. 

Benefits of this treatment

The advantages of the polynucleotide treatment being derived from salon DNA, this product is biocompatible and biodegradable minimising risks of adverse reactions or allergic response. The product has optimal compatibility to humans, if you are worried about having a seafood allergy and me having mentioned the word salmon.. This product is so pure there have been no immunological or allergic responses to the product. 


This injectable treatment is a non-surgical alternative with minimal downtime and discomfort. The treatment is administered much to skin boosters or PRP where we use precise injections to the surface where these small water like injections reduce in the next 3 days. These injections can be tailored to address your specific concern while offering long lasting results with maintenance sessions. 

Ideally Rejuran treatments are performed in an initial treatment course of 3, over 3-4 weeks with maintenance every 6 months. The area will be swollen and lumpy with potential bruising as unfortunately when we are using needles this is always a risk with treatments especially when we are focusing around the eye area. 

In conclusion, Rejuran is offering multiple benefits that extend beyond aesthetic enhancement. Through the unique composition of polynucleotides from Salmon DNA fragments, Rejuran is beneficial in skin rejuvenation, tissue regeneration and wound healing. In the current clinical papers there have been ample improvement, in conjunction with dermal and laser treatments for skin laxity, texture and hydration, all while also addressing fine lines, wrinkles and even shown improvement for acne scarring patients. Its ability to alter the immune response and stimulate collagen synthesis allow great potential for skin ageing and damage. 

With Rejurans consistent efficacy, non-invasive treatment, downtime and safety profile this treatment is taking the world of aesthetics by storm, being a valuable addition to our treatment plans for clients. Patients are reporting a more youthful, radiant complexion and who doesn’t want that? I can imagine the main focus for a lot of clients will be focusing on the laxity and hydration around their eyes which has been giving amazing results so far for all clients involved in using the product. 

It is important to note that individual results and treatment plans do vary, and consultation with one of the medical team at Youth Lab is required to determine the most suitable treatment plan based on individual goals. 

Are you ready for healthier and younger looking skin? I sure am.. Stay tuned for this upcoming treatment at YL. 

See you soon, 

Nurse Lizzie x 

Nurse Lizzie