Dermamelan Depigmentation

Dermamelan is the world's number one treatment for pigmentation. For use in medical clinics only, Youth Lab is the biggest user of Dermamelan in Perth.

Dermamelan is a topical lightening and brightening treatment used to treat all types of pigmentation, from sun spots and freckles to stubborn hormonal melasma.

Suitable for

All skin types concerned with hyperpigmentation or hormonal melasma


$1999, see FAQs below for additional information


2 weeks +


12 months (a second treatment may be needed)


30 minutes

Pregnancy Safe?


applying Dermamelan Depigmentation peel
Pigmentation in the form of sun damage, sun spots, and freckles can often be easily treated by a combination of skin care products, IPL/BBL, laser and chemical peels.

Hormonal pigmentation (melasma) can be much more difficult to treat and can often be made to look worse with some treatments.

The condition can be debilitating and affect self esteem and confidence. Dermamelan is a new and safer alternative to other treatment modalities and can be used effectively in all types of pigmentation, restoring the skin to its natural condition with even tone and brightness.

Dermamelan is the world’s number one treatment for pigmentation. Dermamelan is a topical treatment used to treat all types of pigmentation, from sunspots and freckles to stubborn hormonal melasma which is difficult to treat with other modalities.

As a topical lightening and brightening procedure, Dermamelan is safe to use on all skin types including Asian and Indian skins which often have significant pigmentation that cannot be treated safely with other methods.

It can be used in clients whose pigmentation has not responded to other types of treatments.

before and after Dermamelan Depigmentation peel
before and after Dermamelan Depigmentation peel with grey filter

Dermamelan can be used for many indications including:

  • Melasma (hormonal pigmentation)
  • Sun spots, lentigos and freckles
  • Post inflammatory hyperpigmentation (pigment as a result of previous trauma, infection and other cosmetic procedures)
  • Scarring and discoloration from acne
  • Improvement in skin tone and texture
  • Overall brightening and refinement of the skin
before and after Dermamelan Depigmentation peel front
Dermamelan is a full treatment course consisting of the in-clinic treatment mask, home care products for the 12 week duration of treatment as well as regular in-clinic follow up appointments and healing LED light therapy.

Dermamelan is a medical depigmentation treatment and should only be used under the supervision of a doctor.

Other clinics offer Cosmelan which is the weaker alternative to the treatment. At Youth Lab we only offer Dermamelan with strict doctor’s supervision.


What does the treatment involve?

We recommend a full consultation with one of our doctors, nurses or dermal therapists if you are considering Dermamelan, once a treatment plan has been established the treatment will be booked with one of our Dermal Therapists. The treatment consists of an in clinic phase and a home care phase. 

After cleansing the skin the Dermamelan mask will be applied which feels like a heavy moisturizer. The solution is adjusted according to your concerns and skin type. The mask needs to be left on for 8-12 hours depending on the severity of your pigmentation and skin type. It is best to come into the clinic in the morning so you can relax at home with the mask on during the day.

It is best NOT to sleep with it on. You can then wash off the mask and at this time may feel some tingling and stinging, this is where the work begins with your at home care regime. Your skin will start to feel tight, red and a bit swollen and over the coming days the peeling effect will start. 

The at home phase is the maintenance products that must be used following the in clinic application. We provide very detailed and strict instructions on how to use these products as well as what to expect in the recovery phase.  

How long do results last?

The majority of clients experience a significant improvement after just one treatment. Longer term results are dependent on strict home care (as provided as part of the treatment as well as the recommendations made for maintenance) as well as continued avoidance of sun exposure, triggers for melasma and daily use of broad spectrum SPF.

Many find a repeat treatment at 6 months gives the most optimal results however annual maintenance treatments are also effective. It is very much a case by case basis as every skin responds differently to treating pigmentation.

It is important to remember that hormonal pigmentation (melasma) is a chronic condition with no cure. Dermamelan can control the condition provided triggers and exacerbating factors are avoided by the client.

What happens after my treatment?

Once the mask has been removed at home you may simply go about your normal activities at home. It may be necessary to take time off work and not plan any social events in the few days following the Dermamelan treatment.

Your skin will begin to peel and flake off and may feel very tight and dry, The dryness is generally more evident around the mouth and eyes. Despite the feeling of discomfort, tightness and visible peeling skin it is extremely important not to pick or peel at your skin as this may damage the healthy new skin underneath. 

Strict adherence to the home maintenance program at this time is essential. All the necessary steps will be explained by our dermal therapists and we are always happy to review clients during their Dermamelan journey. 

The results of the treatment can become evident in as soon as 10-14 days with visibly clearer and brighter skin. Ongoing improvement in the skin can be seen over the next month. 

What are the risks of treatment?

Dermamelan has minimal risks and is a very controlled treatment. Many are distressed at the level of downtime which can be intense for some however this is expected and in no way is a complication of treatment.  

There are certain situations where the treatment cannot be performed however this will be discussed at length during your consultation with our cosmetic doctors and dermal therapists. 

Dermamelan cannot be performed if you are pregnant or breastfeeding, have used Roaccutane in the last 6 months, have any active infection or open wounds, have active herpes simplex (cold sores,), have been sunburned recently, have allergies to aspirin or Salicylates, are prone to keloid scarring or have had any cosmetic treatment including laser/BBL/peels/cosmetic injectables in the past 2 weeks.

We also ask patients to avoid any active ingredients in their skin care for the week prior to the treatment. It is important that the full treatment regime be completed in its entirety and no other treatments may be performed during the treatment regime. 

What are the costs?

Dermamelan Depigmentation Course Includes:

  • Full consultation with our Depigmentation specialists
  • In clinic application of the Dermamelan treatment mask 
  • Take home Dermamelan maintenance treatment cream (Value of $398)
  • Take home care products for the 12 week treatment course  (Value of over $560 with 6 Mesoesthetic products)
  • 2 Healite LED treatments and follow-up appointments (Value of over $180)
  • $1999 (over $1197 of added value)